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Dunn School: Notebook 8, Apr 1989–Dec 1991

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MS. 12364/11
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Experiments with radioiodinated T cell epitope peptides (KGoul 2 and 4) and their properties binding to BALB/c and CBA-derived mouse liver microsomes - to test if there is any specificity. Essentially a collaboration with Keith Gould (a post-doctoral researcher) who had characterized several peptide epitopes in the influenza HA and NP proteins, (experiments 124, 126, 149A, 160 with DPhil student Judy Cossins, etc.). Binding and cross-linking experiments. Unsuccessful, as uninterpretable.

Experiments grafting keratinocytes onto skin of mice (experiments 136, 141; 145, 163 both mention DPhil student Ann Gerrard). Aiming to test gene therapy in a human skin-grafted nude mouse model (collaboration with Fiona Watt (ICRF London)). She supplied the human skin cells, the Brownlee lab did the infection and grafting in mice. Experiment 141 mentions Mr. [Jim] Kent - the animal house assistant who helped with the famous penicillin experiments with Norman Heatley in 1939-1940.

Dates

  • Apr 1989–Dec 1991

Extent

1 volume

Language of Materials

  • English

Shelfmark

MS. 12364/11

Repository Details

Part of the Bodleian Libraries Repository

Contact:
Weston Library
Broad Street
Oxford OX1 3BG United Kingdom