Mainly gene therapy experiments; also proposed homologous gene targetting experiments (scheme p. 147): Experiment 44: Rat foetal primary hepatocytes infected with human factor IX retrovirus synthesize human factor IX and is barium precipitable (experiments 46, 54). Experiment 62: Successful PCR, at last, after using precautions to prevent cross-contamination. Experiment...

Experiments with radioiodinated T cell epitope peptides (KGoul 2 and 4) and their properties binding to BALB/c and CBA-derived mouse liver microsomes - to test if there is any specificity. Essentially a collaboration with Keith Gould (a post-doctoral researcher) who had characterized several peptide epitopes in the influenza HA and NP proteins, (experiments 124, 126, 149A, 160 with DPhil student Judy Cossins, etc.). Binding and cross-linking experiments. Unsuccessful, as uninterpretable....