Thatcher was a student of Somerville College Oxford who chose to do her Part II Chemistry with Hodgkin working on gramicidin. She worked as an industrial chemist for a time before reading for the Bar and entering politics. She became leader of the Conservative Party in 1975 and was Prime Minister, 1979-91

Includes draft letter from Hodgkin to Thatcher re Russia 1983 and Hodgkin's recollections of Thatcher at Oxford written for A.L. Hodgkin 1970 and M.A. Epstein 1988.