Simon Hunt was a University Lecturer in the Dunn School from 1974 until he retired in 2012. He came to Oxford to read biochemistry at Trinity College in 1963, and returned to begin a DPhil in that department with Rodney Porter in 1968, after a year's VSO in Antigua.

His project on cell surface proteins on lymphocytes involved collaboration with Jim Gowans, who headed the Cellular Immunology Unit in the Dunn School, and who effectively became a co-supervisor. Hunt applied methods of separating lymphocytes by size so that he could study different populations of immune cells.

He spent a further two years as a post-doc with Gowans before being appointed to the lecturership, and continued to work on the differentiation of T and B cells, using antibodies as markers. Beside his major research interests he collaborated with Henry Harris, Alan Williams and Norman Heatley, who had been a crucial member of the team that developed penicillin. He was given a Lifetime Achievement in Teaching award by the Medical Sciences Division in 2015.