In August 1962, Oxfam's Council of Management proposed the launch of Oxfam in Canada. This extension of Oxfam operated initially as the Canadian Committee for World Relief. In May 1963 the name was changed to Oxfam of Canada. Lynn ten Kate was seconded from Oxford in November 1963 to direct the work. From 1964, Henry Fletcher, Deputy Director of Oxfam in Oxford, made a series of visits to Canada to develop the organization, and in 1966 he left Oxford to take on the directorship of Oxfam Canada, as it became known. He remained in that post until 1971.

It had been agreed that funds raised in Canada for Oxfam's international programme would be channelled through Oxfam in Oxford. From the late 1960s, Oxfam Canada began to assert its independence in funding programme work.

Oxfam Belgique was created in 1964, based in Brussels. This was further developed from late 1966 with the emergence of Oxfam in Gent (Oxfam in Belgium is thus referred to as Oxfam Belgique-België throughout the catalogue). Other Oxfams followed, and some existing agencies, such as Community Aid Abroad in Australia, came to be regarded as national Oxfams. By 1974 the idea of Oxfam International, a worldwide federation of Oxfams with a shared programme and policies, was being formally discussed, though this did not come into being until 1995.

Some of these files contain correspondence with staff in the Oxfam Directorate, the Information Department and other teams. Such files were passed latterly to the Overseas Aid Department / Overseas Directorate.